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Aftin-4
Artikelnummer: TGM-T4364-100mg
Description: Aftin-4, an amyloid forty-two inducer, activates gamma-secretase, promoting the generation of amyloid-beta-1-42 (Abeta1-42) from amyloid-beta protein precursor. Aftin-4(Aftin4) increased Abeta-1-42, but not Abeta-1-40 in mouse hipppocampus, accompanied by learning deficits and mitochondrial...
| Schlagworte: | Aftin 4, Aftin4 |
| Anwendung: | Roscovitine control |
| CAS | 866893-90-5 |
| MW: | 368.48 D |
ab 41,00 €
Aftin-4
Artikelnummer: AG-MR-C0014-M001
Soluble in DMSO or ethanol. Stock solutions can be made up to 10 mM in DMSO. Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells....
| Schlagworte: | N6-Methyl-(R)-roscovitine, Amyloid-beta Forty-Two Inducer 4 |
| Anwendung: | Roscovitine control |
| CAS | 866893-90-5 |
| MW: | 368,5 D |
ab 66,00 €
Aftin-4
Artikelnummer: Cay27341-1
Aftin-4 is an inducer of amyloid-beta (1-42) (Abeta42). It selectively increases extracellular Abeta42 over Abeta40 production in N2a-AbetaPP695 cells when used at concentrations ranging from 1 to 100 mM. In vivo, aftin-4 (3-20 nmol/animal, i.c.v.) increases hippocampal Abeta42 content, lipid peroxidation, and...
| Schlagworte: | 2R-[[9-(1-methylethyl)-6-[methyl(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
| Anwendung: | A-beta42 inducer |
| CAS | 866893-90-5 |
| MW: | 368.5 D |
ab 66,00 €
