Zu "86639-52-3" wurden 3 Artikel gefunden!
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SN-38
Artikelnummer: TGM-T1703-100mg
Description: SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 µM). SN-38 has antitumor activity and induces autophagy. Target: Autophagy, Topoisomerase, DNA/RNA Synthesis, ADC Cytotoxin. Smiles:...
| Schlagworte: | NK012, SN 38 |
| Anwendung: | Topoisomerase I inhibitor |
| CAS | 86639-52-3 |
| MW: | 392.4 D |
ab 39,00 €
SN-38
Artikelnummer: Cay15632-5
SN-38 is an inhibitor of topoisomerase I and an active metabolite of the prodrug irinotecan (Cay-14180). It is formed from irinotecan by carboxylesterases. SN-38 (0.1, 1, and 10 µM) induces topoisomerase I-dependent DNA cleavage in a cell-free assay. It induces DNA single-strand breaks in HT-29 colorectal...
| Schlagworte: | 7-ethyl-10-hydroxy-20(S)-Camptothecin, 7-Ethyl-10-Hydroxycamptothecin, NK 012,... |
| Anwendung: | Potent DNA topoisomerase I inhibitor |
| CAS | 86639-52-3 |
| MW: | 392.4 D |
ab 67,00 €
7-Ethyl-10-hydroxycamptothecin
Artikelnummer: LKT-C0154.10
Camptothecin derivative, topoisomerase I inhibitor.
| Schlagworte: | SN-38, 7-ethyl-10-hydroxy-CPT, 4,11-diethyl-4,9-dihydroxy-1H-Pyrano[3',4':6,7]- indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
| Anwendung: | Topoisomerase I inhibitor |
| CAS | 86639-52-3 |
| MW: | 392.4 D |
ab 208,00 €
