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Belinostat
Artikelnummer: TGM-T8517-100mg
Description: Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity. Target: HDAC, Autophagy. Smiles: S(NC1=CC=CC=C1)(=O)(=O)C2=CC(/C=C/C(NO)=O)=CC=C2. References: Plumb J A , Finn P W , Williams R J , et al....
| Schlagworte: | PXD101, PX105684, PXD-101 |
| Anwendung: | Class I & II HDAC inhibitor |
| CAS | 866323-14-0 |
| MW: | 318.35 D |
ab 40,00 €
Belinostat
Artikelnummer: Cay34084-10
Belinostat is an inhibitor of class I histone deacetylases (HDACs, IC50s = 0.041, 0.125, 0.03, and 0.216 µM for HDAC1, -2, -3, and -8, respectively) and class II HDACs (IC50s = 0.115, 0.082, 0.067, and 0.128 µM for HDAC4, -6, -7, and -9, respectively). It inhibits HDAC activity in HeLa cell lysates (IC50 = 0.027 µM)...
| Schlagworte: | PX 105684, PXD 101, (2E)-N-hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide |
| Anwendung: | Class I & II HDAC inhibitor |
| CAS | 866323-14-0 |
| MW: | 318.3 D |
ab 66,00 €
