Zu "865838-26-2" wurden 2 Artikel gefunden!
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RX-3117
Artikelnummer: Cay27922-1
RX-3177 is a nucleoside derivative and an anticancer agent. It is cytotoxic to HCT116 colorectal, MDA-MB-231 breast, PANC-1 pancreatic, A549 lung, and U251 brain cancer cells (IC50s = 0.39, 0.18, 0.62, 0.34, and 0.83 µM, respectively). RX-3177 (1 and 10 µM) induces DNA damage and apoptosis in A2780 ovarian cancer...
| Schlagworte: | Fluorocyclopentenylcytosine, TV-1360, 4-amino-1-[(1S,4R,5S)-2-fluoro-4,5-dihydroxy-3-(hydroxymethyl)-2-cyclopenten-1-yl]-... |
| Anwendung: | Nucleoside derivative, anticancer agent |
| CAS | 865838-26-2 |
| MW: | 257.2 D |
ab 136,00 €
RX-3117
Artikelnummer: TGM-T16813-100mg
Description: RX-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog. RX-3117 displays anticancer activity in several cancer cell lines, including gemcitabine-resistant variants. Target: Nucleoside Antimetabolite/Analog. Smiles: Nc1ccn([C@H]2[C@H](O)[C@H](O)C(CO)=C2F)c(=O)n1. References: Peters GJ, et al....
| Schlagworte: | fluorocyclopentenylcytosine, TV-1360 |
| Anwendung: | Targets DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] (DNMT1, dcm) |
| CAS | 865838-26-2 |
| MW: | 257.22 D |
ab 159,00 €
