Zu "865231-46-5" wurden 2 Artikel gefunden!
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AMG 837
Artikelnummer: TGM-T14216-10mg
Description: AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound excels as a GPR40 agonist with a notable pharmacokinetic profile, effectively...
| Anwendung: | Partial GPR40 agonist |
| CAS | 865231-46-5 |
| MW: | 438.44 D |
ab 93,00 €
AMG 837
Artikelnummer: Cay21815-5
AMG 837 is a partial agonist of free fatty acid receptor 1 (FFAR1/GPR40). It induces calcium mobilization in CHO cells expressing FFAR1/GPR40 but not FFAR2/GPR43, FFAR3/GPR41, or FFAR4/GPR120 (EC50s = 0.0135, >10, >10, and >10 µM, respectively). AMG 837 induces insulin secretion in MIN6 pancreatic beta-cells and...
| Schlagworte: | betaS-1-propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-benzenepropanoic acid |
| Anwendung: | Partial GPR40 agonist |
| CAS | 865231-46-5 |
| MW: | 438.4 D |
ab 52,00 €
