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FSEN1
FSEN1

Artikelnummer: TGM-T77765-100mg

Description: FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM. FSEN1 induces ferroptosis in cancer cells by inhibiting FSP1. FSEN1 can be used to prevent and treat cancer. Target: Ferroptosis. Smiles: COC1=CC=C(C=C1)N1CCN(CC2=CN3C(S2)=NN=C3C2=CC=C(Br)C=C2)CC1....
Schlagworte: 3-(4-bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole
Anwendung: FSP1 (AIFM2) inhibitor
CAS 862808-01-3
MW: 484.41 D
ab 44,00 €
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FSEN1
FSEN1

Artikelnummer: Cay38025-5

FSEN1 is an inhibitor of ferroptosis suppressor protein 1 (FSP1, IC50 = 313 nM). It is selective for FSP1 over NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1, IC50 = >100 µM). FSEN1 induces cell death in GPX4-/- H460 non-small cell lung cancer (NSCLC) cells (EC50 = 69.36 nM) but not control H460 cells expressing...
Schlagworte: Ferroptosis Sensitizer 1, 3-(4-bromophenyl)-6-[[4-(4-methoxyphenyl)-1-piperazinyl]methyl]-thiazolo[2,3-c]-1,2,4-triazole
Anwendung: FSP1 (AIFM2) inhibitor
CAS 862808-01-3
MW: 484.4 D
ab 39,00 €
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