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Lenvatinib mesylate
Artikelnummer: TGM-T8541-100mg
Description: Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities. Target: FGFR, c-Kit, VEGFR, PDGFR, c-RET. Smiles: CS(O)(=O)=O.COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O. References: Suyama K, et al....
| Schlagworte: | E7080 (mesylate) |
| Anwendung: | Targets FMS-like tyrosine kinase 1 [EC:2.7.10.1] (FLT1, VEGFR1) |
| CAS | 857890-39-2 |
| MW: | 522.96 D |
ab 34,00 €
Lenvatinib (mesylate)
Artikelnummer: Cay29832-500
Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and KIT (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
| Schlagworte: | E-7080, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide, monomethanesulfonate |
| Anwendung: | VEGFR2 / VEGFR3 inhibitor |
| CAS | 857890-39-2 |
| MW: | 523 D |
ab 115,00 €
