Zu "853910-02-8" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
NVP-BAG956
Artikelnummer: TGM-TQ0313-100mg
Description: NVP-BAG956 is an ATP-competitive PI3K inhibitor with IC50 values of 34 nM for PI3Kdelta, 56 nM for PI3Kalpha, 112 nM for PI3Kgamma, and 444 nM for PI3Kbeta. Target: PI3K. Smiles: Cc1nc2cnc3ccc(cc3c2n1-c1ccc(cc1)C(C)(C)C#N)C#Cc1cccnc1. References: Marone R, et al. Targeting melanoma with dual...
| Schlagworte: | BAG956 |
| Anwendung: | PDK1 inhibitor, PI3K inhibitor |
| CAS | 853910-02-8 |
| MW: | 427.5 D |
ab 747,00 €
NVP-BAG956
Artikelnummer: Cay24195-1
NVP-BAG956 is a dual inhibitor of 3-phosphoinositide-dependent protein kinase 1 (PDK1, IC50 = 245 nM) and class I phosphatidylinositol 3-kinase catalytic subunits (PI3Ks, IC50s = 56, 446, 35, and 117 nM for p110alpha, p110beta, p110delta, and p110gamma, respectively). It inhibits phosphorylation of T308-PKB (IC50 =...
| Schlagworte: | BAG956, alpha,alpha-dimethyl-4-[2-methyl-8-[2-(3-pyridinyl)ethynyl]-1H-imidazo[4,5-c]quinolin-1-yl]-benzeneacetonitrile |
| Anwendung: | PDK1 inhibitor, PI3K inhibitor |
| CAS | 853910-02-8 |
| MW: | 427.5 D |
ab 52,00 €
