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PF-00489791
Artikelnummer: TGM-T28360-10mg
Description: PF-00489791 (PF4634817) is a long-acting PDE5 inhibitor with hypotensive activity for the study of diabetic nephropathy. Target: PDE. Smiles: C(NS(C)(=O)=O)(=O)C=1C=2C(=C(NC3=CC(C)=CC=N3)N=C(N(CC)C)N2)N(CCOCC)N1. References: Scheele W, Diamond S, Gale J, Clerin V, Tamimi N, Le V, Walley R, Grover-Páez...
| Schlagworte: | PF4634817, PF 00489791, PF-4634817, PF 4634817, PF00489791 |
| Anwendung: | PDE5A inhibitor |
| CAS | 853003-48-2 |
| MW: | 476.55 D |
ab 103,00 €
PF-00489791
Artikelnummer: Cay40464-1
PF-00489791 is an inhibitor of phosphodiesterase 5A (PDE5A, IC50 = 1.9 nM). It does not cross the blood-brain barrier in rats. PF-00489791 (10 mg/kg) improves motor scores in a rat model of stroke induced by middle cerebral artery occlusion (MCAO).Formal Name:...
| Schlagworte: | PF-489791, UK 489791,... |
| Anwendung: | PDE5A inhibitor |
| CAS | 853003-48-2 |
| MW: | 476.6 D |
ab 39,00 €
