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CMP8
Artikelnummer: TGM-T14987-100mg
Description: CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERalpha, MGRERalpha, hERalpha and hERbeta, respectively. Target: Estrogen/progestogen Receptor, Estrogen...
| Anwendung: | Mutant ERalpha antagonist, bump and hole ligand |
| CAS | 851107-28-3 |
| MW: | 528.08 D |
ab 247,00 €
CMP8
Artikelnummer: Cay36585-1
CMP8 is a mutant estrogen receptor alpha (ERalpha) antagonist and ligand used for bump and hole, a technique to study single protein isoforms when familial homology would interfere with other isoform-selective approaches. It is selective for an ERalpha triple mutant containing a lysine-to-methionine substitution at...
| Schlagworte: | 9a-[(4-chlorophenyl)methyl]-1,2,9,9a-tetrahydro-7-hydroxy-4-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3H-fluoren-3-one |
| Anwendung: | Mutant ERalpha antagonist, bump and hole ligand |
| CAS | 851107-28-3 |
| MW: | 528.1 D |
ab 43,00 €
