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Delanzomib [CEP-18770]
Delanzomib [CEP-18770]

Artikelnummer: AG-CR1-3673-M005

Synthetic. Chemical. CAS: 847499-27-8. Formula: C21H28BN3O5. MW: 413.3. Synthetic. Potent, selective, reversible orally bioavailable proteasome inhibitor. Synthetic P2 threonine boronic acid. Targets the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome (IC50=3.8nM). Cross-reacts and inhibits the...
Schlagworte: NPH 007098, CT 47098, CIP 18770,...
Anwendung: Proteasome inhibitor
CAS 847499-27-8
MW: 413,3 D
ab 33,00 €
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Delanzomib
Delanzomib

Artikelnummer: Cay23557-1

Delanzomib is an orally bioavailable inhibitor of chymotrypsin-like proteasome activity (IC50 = 3.8 nM in isolated human erythrocytes) that only marginally inhibits tryptic and peptidyl glutamyl proteasome activity. Delanzomib pre-treatment (20 nM) in vitro inhibits IkappaBalpha degradation, NF-kappaB activation,...
Schlagworte: CEP-18770,...
Anwendung: Antineoplastic, Proteasome inhibitor
CAS 847499-27-8
MW: 413.3 D
ab 43,00 €
Bewerten