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Bretazenil
Bretazenil

Artikelnummer: Cay28411-5

Bretazenil is a positive allosteric modulator of GABAA receptors with anticonvulsant and anxiolytic activity. It potentiates GABA-gated chloride currents in rat cortical neurons and in HEK293 cells expressing alpha1beta1gamma2 subunit-containing GABAA receptors (EC50s = 60 and 10 nM, respectively). Bretazenil...
Schlagworte: Ro 16-6028, (13aS)-8-bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic...
Anwendung: GABA-A receptor positive allosteric modulator
CAS 84379-13-5
MW: 418.3 D
ab 50,00 €
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Bretazenil
Bretazenil

Artikelnummer: Cay37274-1

Bretazenil (Cay-37274) is an analytical reference standard categorized as a GABAA receptor positive allosteric modulator. Bretazenil has anxiolytic-like effects in mice. It induces self-administration in rhesus monkeys but has a lower physical dependence liability in mice compared with benzodiazepines. This product...
Schlagworte: Ro 16-6028, 8-bromo-11,12,13,13aS-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][1,4]benzodiazepine-1-carboxylic acid,...
Anwendung: Analytical reference standard, GABA-A receptor positive allosteric modulator
CAS 84379-13-5
MW: 418.3 D
ab 158,00 €
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