Zu "842133-18-0" wurden 2 Artikel gefunden!
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Canagliflozin
Artikelnummer: TGM-T1782-100mg
Description: Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM). Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM). Target: SGLT. Smiles:...
| Schlagworte: | JNJ 24831754ZAE, JNJ 28431754AAA, TA 7284, JNJ 28431754 |
| Anwendung: | SGLT2 inhibitor |
| CAS | 842133-18-0 |
| MW: | 444.52 D |
ab 45,00 €
Canagliflozin
Artikelnummer: Cay11575-5
Canagliflozin is an inhibitor of sodium-glucose cotransporter 2 (SGLT2, IC50 = 2.2 nM) that less potently blocks SGLT1 (IC50 = 910 nM). Canagliflozin is orally bioavailable and lowers plasma glucose by lowering the renal threshold for glucose and increasing urinary glucose excretion in animals. Formulations...
| Schlagworte: | JNJ-24831754, TA-7284, (1S)-1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol |
| Anwendung: | SGLT2 inhibitor |
| CAS | 842133-18-0 |
| MW: | 444.5 D |
ab 78,00 €
