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WIKI4
Artikelnummer: TGM-T3062-100mg
Description: WIKI4 is a potent inhibitor of Wnt/beta-catenin signaling and tankyrase 2 (TNKS2). Target: PARP, Wnt/beta-catenin. Smiles: COc1ccc(cc1)-n1c(SCCCN2C(=O)c3cccc4cccc(C2=O)c34)nnc1-c1ccncc1. References: James RG, et al. PLoS One. 2012, 7(12), e50457.
| Anwendung: | Tankyrase inhibitor |
| CAS | 838818-26-1 |
| MW: | 521.59 D |
ab 34,00 €
WIKI4
Artikelnummer: Cay14057-10
Tankyrases (TNKS) cleave NAD+ to produce nicotinamide and ADP-ribose, which is then covalently attached to an acceptor protein in the process known as poly(ADP-ribosyl)ation. WIKI4 is a potent and selective inhibitor of TNKS1 and TNKS2 (IC50s = 26 and 15 nM, respectively). It has little or no effect on related...
| Schlagworte: | Tankyrase 1/2 Inhibitor V,... |
| Anwendung: | Tankyrase inhibitor |
| CAS | 838818-26-1 |
| MW: | 521.6 D |
ab 128,00 €
