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AS1842856
Artikelnummer: TGM-T6762-100mg
Description: AS1842856, a cell-permeable inhibitor, can block the transcription activity of Foxo1 (IC50: 33 nM). It can directly bind to the active Foxo1, but not the Ser256-phosphorylated form. Target: FOXO1, Autophagy. Smiles: CCn1cc(C(O)=O)c(=O)c2c(N)c(F)c(NC3CCCCC3)cc12. References: Takeyuki Nagashima,et al.Mol...
| Anwendung: | Foxo1 Inhibitor |
| CAS | 836620-48-5 |
| MW: | 347.38 D |
ab 46,00 €
AS-1842856
Artikelnummer: Cay16761-1
AS-1842856 is a potent inhibitor of forkhead box class O transcription factor 1 (FoxO1, IC50 = 33 nM in HepG2 cells). Inhibition of FoxO1-mediated transactivation with AS-1842856 leads to a dose-dependent decrease in expression of glucose-6 phosphatase (G6Pase) and phosphoenolpyruvate carboxykinase (PEPCK) mRNA and...
| Schlagworte: | FOXO1 Inhibitor, 5-amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid |
| Anwendung: | Foxo1 Inhibitor |
| CAS | 836620-48-5 |
| MW: | 347.4 D |
ab 43,00 €
