Zu "827022-32-2" wurden 3 Artikel gefunden!
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Palbociclib monohydrochloride
Artikelnummer: TGM-T6239-100mg
Description: Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition against a panel of 36 additional protein kinases. Target: CDK. Smiles: Cl.CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n(C2CCCC2)c1=O. References: Fry DW, et al. Specific...
| Schlagworte: | PD 0332991 hydrochloride, Palbociclib hydrochloride, Palbociclib (PD-0332991) HCl |
| Anwendung: | Cyclin-dependent kinase 4/6 (CDK4/6) inhibitor |
| CAS | 827022-32-2 |
| MW: | 483.99 D |
ab 50,00 €
PD 0332991 (hydrochloride)
Artikelnummer: Cay16273-1
PD 0332991 is an orally active, selective inhibitor of the cyclin D kinases Cdk4 (IC50 = 11 nM) and Cdk6 (IC50= 16 nM) with no activity against a panel of 36 additional protein kinases. It has been reported to have antiproliferative activity against retinoblastoma-positive tumor cells, blocking retinoblastoma...
| Schlagworte: | Palbociclib, 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one,... |
| Anwendung: | Cyclin-dependent kinase 4/6 (CDK4/6) inhibitor |
| CAS | 827022-32-2 |
| MW: | 484 D |
ab 50,00 €
Palbociclib Hydrochloride
Artikelnummer: LKT-P0244.5
Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. PD-0332991 selectively inhibits cyclin-dependent kinases (particularly Cdk4/cyclin D1 kinase), which may inhibit retinoblastoma (Rb) protein...
| Schlagworte: | PD-033291, PD0332991,... |
| Anwendung: | Cdk4 / Cdk6 inhibitor |
| CAS | 827022-32-2 |
| MW: | 484 D |
ab 60,00 €
