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Concanamycin B
Artikelnummer: TGM-T36116-1mg
Description: Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases (IC50 = 5 nM), thereby blocking vacuolar organelle acidification and early to late endosomal transport. It interferes with bone resorption, maturation of CD8 T lymphocytes, and prevents processing of major...
| Anwendung: | Macrolide-type antibiotic, V-ATPase inhibitor |
| CAS | 81552-33-2 |
| MW: | 852.072 D |
1.859,00 €
Concanamycin B
Artikelnummer: BVT-0253-C025
Antibiotic, Exhibits similar activity as concanamycin A (Prod. No. BVT-0237) and concanamycin C (Prod. No. BVT-0254), Specific vacuolar-type H+ATPase inhibitor, Suppresses bone resorption, Inhibits proliferation of mouse splenic lymphocytes, Antifungal and larvicidal. Isolated from Streptomyces sp.
| Schlagworte: | 8-Deethyl-8-methylconcanamycin A |
| Anwendung: | H+ATPase inhibitor |
| CAS | 81552-33-2 |
| MW: | 852,1 D |
ab 85,00 €
Concanamycin B
Artikelnummer: Cay15502-1
Concanamycin B is a macrolide antibiotic originally isolated from Streptomyces that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). In this way, it blocks the acidification of vacuolar organelles as well as early to late endosomal transport. Concanamycin B interferes with bone...
| Schlagworte: | 8-deethyl-8-methyl-Concanamycin A, MCH 210,... |
| Anwendung: | Macrolide-type antibiotic, V-ATPase inhibitor |
| CAS | 81552-33-2 |
| MW: | 852.1 D |
ab 302,00 €
