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AR7
AR7

Artikelnummer: TGM-T3955-100mg

Description: AR7 is a retinoic acid receptor alpha (RARalpha) antagonist. Target: Retinoid Receptor. Smiles: Cc1ccc(cc1)C1=Nc2ccc(Cl)cc2OC1. References: Anguiano J, et al. Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives. Nat Chem Biol. 2013 Jun,9(6):374-82.
Anwendung: Retinoic acid receptor alpha agonist
CAS 80306-38-3
MW: 257.71 D
ab 32,00 €
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AR-7
AR-7

Artikelnummer: Cay22946-1

AR-7 is a retinoic acid receptor alpha (RARalpha) antagonist. In mouse fibroblasts, AR-7 (20 µM) increases chaperone-mediated autophagy in an RARalpha-dependent manner, increases LAMP-2A expression, and inhibits paraquat-induced decreases in cell viability. AR-7 is also selectively cytotoxic to HepG2 cells grown...
Schlagworte: 7-chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine
Anwendung: Retinoic acid receptor alpha agonist
CAS 80306-38-3
MW: 257.7 D
ab 43,00 €
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