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ABT-869
ABT-869

Artikelnummer: Cay13653-1

ABT-869 is a dual VEGFR and PDGFR family kinase inhibitor (IC50s = 0.003, 0.004, 0.004, 0.19, 0.066, 0.003, and 0.014 µM for VEGFR1, VEGFR2, FLT3, VEGFR3, PDGFRbeta, CSF-1R, and KIT, respectively). It is selective for these kinases over other tyrosine kinases, including RET, FGFR, Src, EGFR, and c-Met (IC50s = 1.9,...
Schlagworte: Linifanib, N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)-urea
Anwendung: RTK inhibitor
CAS 796967-16-3
MW: 375.4 D
ab 55,00 €
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Linifanib
Linifanib

Artikelnummer: SYN-1002-M001

Soluble in DMSO or ethanol. Linifanib (A 741439, A-741439, A741439, ABT-869, ABT869, RG3635) is an orally active multi-targeted receptor tyrosine kinase inhibitor for the treatment of various cancers. The compound is designed to inhibit vascular endothelial growth factor and platelet-derived growth factor receptors...
Schlagworte: ABT-869, AL39324, RG-3635
Anwendung: PDGFR / VEFGR inhibitor
CAS 796967-16-3
MW: 375,4 D
ab 123,00 €
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