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KYP-2047
Artikelnummer: TGM-T8657-100mg
Description: KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor. Target: Others. Smiles: C(=O)([C@H]1N(C(CCCC2=CC=CC=C2)=O)CCC1)N3[C@H](C#N)CCC3. References: T T Myöhänen 1 , M J Hannula, R Van Elzen,et al.A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and...
| Anwendung: | Prolyl endopeptidase inhibitor |
| CAS | 796874-99-2 |
| MW: | 339.43 D |
ab 45,00 €
KYP-2047
Artikelnummer: Cay39180-1
KYP-2047 is an inhibitor of prolyl endopeptidase (Ki = 0.02 nM for the porcine enzyme). It inhibits hydrogen peroxide-induced aggregation of alpha-synuclein in SH-SY5Y cells expressing wild-type, alpha-synucleinA30P, or alpha-synucleinA53T in in vitro models of Parkinson's disease when used at a concentration of 1...
| Schlagworte: | (2S)-1-[[(2S)-1-(1-oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile |
| Anwendung: | Prolyl endopeptidase inhibitor |
| CAS | 796874-99-2 |
| MW: | 339.4 D |
ab 80,00 €
