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Milrinone
Artikelnummer: LKT-M3344.10
A selective phospodiesterase 3 inhibitor known to effect left ventricular relaxation by inhibiting the breakdown of cAMP in association with an acceleration of sarcoplasmic reticulum Ca(2)-ATP activity and CA(2) uptake. It inhibits platelet aggregation and induces disaggregation.
| Anwendung: | Phosphodiesterase 3 inhibitor |
| CAS | 78415-72-2 |
| MW: | 211,22 D |
ab 177,00 €
Milrinone
Artikelnummer: Cay13357-5
Milrinone is an inhibitor of type 3 phosphodiesterases (PDEs), inhibiting recombinant PDE3A and PDE3B with IC50 values of 0.45 and 1 µM, respectively. It is selective for PDE3 over PDE1, PDE2, PDE4, PDE5, and PDE7 (IC50s = 263, >300, 17.5, 49.1, and 58.3 µM, respectively). Milrinone (0.1-1 mg/kg) has positive...
| Schlagworte: | WIN 47,203, 1,6-dihydro-2-methyl-6-oxo-[3,4'-bipyridine]-5-carbonitrile |
| Anwendung: | PDE3 inhibitor |
| CAS | 78415-72-2 |
| MW: | 211.2 D |
ab 109,00 €
