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Latrunculin A
Artikelnummer: Cay10010630-100
Actin disruption is used to study cell functions in vitro (e.g., migration, endocytosis) and in vivo (e.g., tumor cell invasion). Latrunculin A is a bioactive 2-thiazolidinone macrolide derived from sponges that sequesters G-actin and prevents F-actin assembly. It binds monomeric actin with 1:1 stoichiometry and can...
| Schlagworte: | NSC 613011,... |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-93-6 |
| MW: | 421.6 D |
ab 66,00 €
Latrunculin A
Artikelnummer: TGM-T15721-1mg
Description: Latrunculin A is a toxin isolated from the red sea sponge Latrunculia magnifica. Latrunculin A binds to actin monomers and it also inhibits polymerization of actin (Kds: 0.1, 0.4, 4.7 µM, and 0.19 µM for ATP-actin, ADP-Pi-actin, ADP-actin, and G-actin, respectively). Target: Others. Smiles:...
| Schlagworte: | LAT-A |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-93-6 |
| MW: | 421.55 D |
2.313,00 €
Latrunculin A
Artikelnummer: AG-CN2-0027-C100
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Potent phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in...
| Schlagworte: | LAT-A, NSC 613011 |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-93-6 |
| MW: | 421,6 D |
ab 138,00 €
