Zu "763113-22-0" wurden 4 Artikel gefunden!
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Olaparib
Artikelnummer: Cay10621-5
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM,...
| Schlagworte: | AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
| Anwendung: | PARP1 / PARP2 inhibitor |
| CAS | 763113-22-0 |
| MW: | 434.5 D |
ab 66,00 €
Olaparib
Artikelnummer: TGM-T3015-100mg
Description: Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 µM), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity. Target: PARP, Mitophagy, Autophagy....
| Schlagworte: | KU0059436, AZD2281 |
| Anwendung: | Targets poly [ADP-ribose] polymerase 1 [EC:2.4.2.30] (PARP1) |
| CAS | 763113-22-0 |
| MW: | 434.46 D |
ab 32,00 €
Olaparib
Artikelnummer: LKT-O4402.5
A potent orally active inhibitor of PARP (Poly(adenosine diphosphate-ribose) polymerase)-1 and PARP-2.
| Schlagworte: | AZD2281, KU-0059436 |
| Anwendung: | Poly(adenosine diphosphate-ribose) polymerase inhibitor |
| CAS | 763113-22-0 |
| MW: | 434,47 D |
ab 108,00 €
Olaparib
Artikelnummer: CDX-O0144-G001
Off-white to beige powder. Soluble in DMSO (20mg/ml) or DMF (10mg/ml). Slightly soluble in ethanol (1mg/ml). Chemical. CAS: 763113-22-0. Formula: C24H23FN4O3. MW: 434.47. Synthetic. Olaparib is a cell-permable potent inhibitor of PARP1 and PARP2 (IC50=5 and 1nM, respectively) but is less effective against the PARP...
| Schlagworte: | AZD 2281, Ku-0059436, Lynparza,... |
| CAS | 763113-22-0 |
| MW: | 434,47 D |
ab 122,00 €
