Zu "755037-03-7" wurden 5 Artikel gefunden!
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Regorafenib
Artikelnummer: Cay18498-5
Regorafenib is an orally bioavailable multi-kinase inhibitor with anticancer activity. It inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRbeta with IC50 values of 1.5, 2.5, 4.2, 7, 13, and 22 nM, respectively. Regorafenib also inhibits B-RAF, VEGFR3, FGFR, and Tie2 (IC50s = 28, 46, 202, and 311 nM, respectivey)...
| Schlagworte: | BAY 73-4506,... |
| Anwendung: | VEGFR inhibitor |
| CAS | 755037-03-7 |
| MW: | 482.8 D |
ab 60,00 €
Regorafenib
Artikelnummer: SYN-1169-M100
Soluble in DMSO or ethanol. Regorafenib (BAY 73-4506, Fluoro-Sorafenib) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFR beta, Kit, RET and Raf-1 with IC(50) values of 13, 4.2, 46, 22, 7, 1.5 and 2.5nM, respectively. Target: VEGFR , Kinase Group: RTK , Substrate: Tyrosine
| Schlagworte: | BAY-73-4506 |
| Anwendung: | VEGFR2 / RET / Raf-1 inhibitor |
| CAS | 755037-03-7 |
| MW: | 482,8 D |
Bitte fragen Sie den aktuellen Preis für diesen Artikel an.
![Regorafenib [BAY 73-4506]](https://www.biomol.com/media/image/de/e2/97/AG-CR1-3623-M005_200x200.png "Regorafenib [BAY 73-4506]")
Regorafenib [BAY 73-4506]
Artikelnummer: AG-CR1-3623-M025
Light pink to white solid. Soluble in DMSO (>50mg/ml). Slightly soluble in ethanol (1mg/ml). Insoluble in water. Orally bioavailable potent antitumor, antiangiogenic, antiproliferative and antineoplastic agent, Multi-target kinase inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRbeta, Kit, RET and Raf-1 with IC50 values of...
| Schlagworte: | BAY 73-4506, Fluoro-Sorafenib |
| Anwendung: | VEGFR1/2/3/PDGFRbeta/Kit/RET/Raf-1 inhibitor |
| CAS | 755037-03-7 |
| MW: | 482,8 D |
ab 39,00 €
Regorafenib
Artikelnummer: LKT-R1626.1
Regorafenib is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor...
| Schlagworte: | BAY73-4506, BAY 73-4506, BAY734506, 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide |
| Anwendung: | VEGFR2/3 / Ret inhibitor |
| CAS | 755037-03-7 |
| MW: | 500.83 D |
ab 60,00 €
Regorafenib Anhydrous
Artikelnummer: LKT-R1627.1
Multikinase inhibitor.
| Schlagworte: | BAY73-4506 |
| Anwendung: | VEGFR1 / VEGFR3 / PDGFRB / FGFR1 inhibitor |
| CAS | 755037-03-7 |
| MW: | 482.82 D |
ab 63,00 €
