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EHT 1864
Artikelnummer: TGM-T6483-100mg
Description: EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3 (Kd=40/50/60/250 nM). EHT 1864 inhibits Rac, Ras, and Tiam-induced growth transformation of NIH-3T3 fibroblasts. Target: Rho, Ras. Smiles:...
| Schlagworte: | EHT 1864 2HCl |
| Anwendung: | Rac inhibitor |
| CAS | 754240-09-0 |
| MW: | 581.47 D |
ab 40,00 €
EHT 1864
Artikelnummer: Cay17258-1
EHT 1864 is an inhibitor of the Rac subfamily of Rho GTPases, that binds to Rac1, Rac1b, Rac2, and Rac3 with Kd values of 40, 50, 50, and 250 nM, respectively. It can reverse transformation of NIH 3T3 fibroblasts caused by constitutively activated Rac1, as well as Rac-dependent transformation caused by Tiam1 or Ras....
| Schlagworte: | 2-(4-morpholinylmethyl)-5-[[5-[[7-(trifluoromethyl)-4-quinolinyl]thio]pentyl]oxy]-4H-pyran-4-one, dihydrochloride |
| Anwendung: | Rac inhibitor |
| CAS | 754240-09-0 |
| MW: | 581.5 D |
ab 44,00 €
