Zu "747412-49-3" wurden 3 Artikel gefunden!
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Luminespib
Artikelnummer: TGM-T1989-100mg
Description: Luminespib (VER-52296) is a novel HSP90 inhibitor with IC50 values of 7.8 nM for HSP90alpha and 21 nM for HSP90beta in a cell-free assay. Target: HSP, Apoptosis, Autophagy. Smiles: CCNC(=O)c1noc(c1-c1ccc(CN2CCOCC2)cc1)-c1cc(C(C)C)c(O)cc1O. References: Eccles, Suzanne A., et al. NVP-AUY922: A Novel...
| Schlagworte: | NVP-AUY922, VER-52296, AUY922 |
| Anwendung: | Antineoplastic, Hsp 90 inhibitor |
| CAS | 747412-49-3 |
| MW: | 465.54 D |
ab 52,00 €
NVP-AUY922
Artikelnummer: Cay10012698-5
Hsp90 is a molecular chaperone of many different kinases, transcription factors, and hormone receptors involved in signal transduction, cell cycle regulation, and apoptosis. In addition to its important function in normal cell homeostasis, a high affinity form of Hsp90 is prevalent in tumor cells. Hsp90 inhibition...
| Schlagworte: | VER 52296, 5-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-N-ethyl-4-[4-(4-morpholinylmethyl)phenyl]-3-isoxazolecarboxamide |
| Anwendung: | Hsp90 Inhibitor |
| CAS | 747412-49-3 |
| MW: | 465.5 D |
ab 209,00 €
NVP-AUY922
Artikelnummer: LKT-N8660.1
Isoxazole derivative, HSP90 inhibitor.
| Schlagworte: | VER-52296 |
| Anwendung: | Isoxazole derivative, HSP90 inhibitor |
| CAS | 747412-49-3 |
| MW: | 465.54 D |
ab 109,00 €
