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GSK356278
Artikelnummer: TGM-T27475-100mg
Description: GSK356278 is an effective and selective inhibitor of phosphodiesterase 4 (PDE4), with pIC50s of 8.6, 8.8, and 8.7 for human PDE4A, PDE4B, and PDE4D, respectively. GSK356278 has anti-inflammatory, anxiolytic, and cognition-enhancing effects. Target: PDE. Smiles:...
| Schlagworte: | GSK-356278, GSK 356278 |
| Anwendung: | Potent, selective PDE4 inhibitor |
| CAS | 720704-34-7 |
| MW: | 439.53 D |
ab 34,00 €
GSK356278
Artikelnummer: Cay30412-10
GSK356278 is a potent, selective, and orally bioavailable phosphodiesterase 4 (PDE4) inhibitor with anxiolytic and cognition-improving effects. It is greater than 100-fold selective for PDE4A, -B, and -D (IC50s = 2.51, 1.58, and 2 nM for PDE4A, PDE4B, and PDE4D, respectively) over 10 other members of the PDE family,...
| Schlagworte: | 5-[5-[(2,4-dimethyl-5-thiazolyl)methyl]-1,3,4-oxadiazol-2-yl]-1-ethyl-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-b]pyrid... |
| Anwendung: | Potent, selective PDE4 inhibitor |
| CAS | 720704-34-7 |
| MW: | 439.5 D |
ab 77,00 €
