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Alizarin
Alizarin

Artikelnummer: TGM-T2949-1g

Description: Alizarin (Mordant Red 11), a red dye derived from the roots of plants of the madder genus, inhibits P450 isoform CYP1A1( IC50 = 6.2 µM), CYP1A2 (IC50 =10.0 µM )and CYP1B1(IC50 = 2.7 µM). Target: P450. Smiles: OC1=C(O)C2=C(C=C1)C(=O)C1=CC=CC=C1C2=O. References: Takahashi E, et al. Mutat Res, 2002,...
Schlagworte: Mordant Red 11, Anthraquinonic
Anwendung: CYP1A1 / CYP1A2 / CYP1B1 inhibitor
CAS 72-48-0
MW: 240.21 D
ab 46,00 €
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Alizarin
Alizarin

Artikelnummer: Cay11676-50

Alizarin is a small molecule inhibitor of cytochrome P450 isoforms CYP1A1, CYP1A2, and CYP1B1 (IC50s = 6.2, 10, and 2.7 µM, respectively). Alizarin acts as an antioxidant against iodophenol-derived phenoxyl radicals, superoxide anion radicals, and lipid peroxidation in rat liver microsomes. It also reduces hepatic...
Schlagworte: CI-58000, NSC 7212, 1,2-dihydroxy-9,10-anthracenedione
Anwendung: CYP1A1 / CYP1A2 / CYP1B1 inhibitor
CAS 72-48-0
MW: 240.2 D
ab 43,00 €
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