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Saxagliptin hydrochloride
Artikelnummer: TGM-T6203L-5mg
Description: Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in...
| Schlagworte: | Saxagliptin HCl, BMS-477118, Saxagliptin, BMS477118, BMS 477118 |
| Anwendung: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 709031-78-7 |
| MW: | 351.87 D |
951,00 €
Saxagliptin (hydrochloride)
Artikelnummer: Cay23697-5
Saxagliptin is a potent inhibitor of dipeptidyl peptidase 4 (DPP-4, Ki = 0.6 nM). It inhibits DPP-4 ex vivo (ED50 = 0.12 µmol/kg) in plasma from normal fasted rats. Saxagliptin (0.3-3 mg/kg) reduces plasma glucose levels in Zuckerfa/fa diabetic rats in a dose-dependent manner. Oral administration at doses ranging...
| Schlagworte: | BMS-477118,... |
| Anwendung: | Dipeptidyl peptidase-4 (DPP-4) inhibitor |
| CAS | 709031-78-7 |
| MW: | 351.9 D |
ab 54,00 €
