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Mitoxantrone (hydrochloride)
Mitoxantrone (hydrochloride)

Artikelnummer: Cay14842-10

Mitoxantrone is an inhibitor of DNA topoisomerase IIalpha and HIV-1 integrase (IC50s = 5.3 and 3.8 µM, respectively). It intercalates into DNA in a cell-free assay when used at a concentration of 2 µM, as well as inhibits DNA synthesis and induces DNA-protein crosslinks in vitro in a concentration-dependent manner....
Schlagworte: NCI 301739, NSC 301739, 1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione, dihydrochloride
Anwendung: Topoisomerase II inhibitor, HIV-1 integrase inhibitor
CAS 70476-82-3
MW: 517.4 D
ab 43,00 €
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Mitoxantrone Dihydrochloride
Mitoxantrone Dihydrochloride

Artikelnummer: LKT-M3379.50

A cytostatic anthraquinone derivative. An antitumor agent that interacts with DNA by intercallation.
Anwendung: Anticancer agent
CAS 70476-82-3
MW: 517,41 D
ab 175,00 €
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