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IWP-3
Artikelnummer: TGM-T21650-100mg
Description: IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1gamma3 and CK1epsilon, but does not inhibit CK1alpha [1] [2]. Target: Wnt/beta-catenin. Smiles:...
| Anwendung: | Porcupine inactivator |
| CAS | 687561-60-0 |
| MW: | 484.59 D |
ab 40,00 €
IWP-3
Artikelnummer: Cay13953-1
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to beta-catenin activation of gene transcription. IWP-3 is an inhibitor of Wnt production...
| Schlagworte: | Inhibitor of Wnt Production-3,... |
| Anwendung: | Porcupine inactivator |
| CAS | 687561-60-0 |
| MW: | 484.6 D |
ab 53,00 €
