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IWP-4
Artikelnummer: TGM-T4245-100mg
Description: IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor. Target: Wnt/beta-catenin. Smiles: COc1ccccc1-n1c(SCC(=O)Nc2nc3ccc(C)cc3s2)nc2CCSc2c1=O. References: Lian X, et al. Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling....
| Schlagworte: | Inhibitor of Wnt Production-4 |
| Anwendung: | Wnt production inhibitor, porcupine inactivator |
| CAS | 686772-17-8 |
| MW: | 496.62 D |
ab 42,00 €
IWP-4
Artikelnummer: Cay13954-1
IWP-4 is an inhibitor of Wnt production that impairs Wnt pathway activity in vitro with an IC50 value of 25 nM. IWP-4 inactivates Porcupine, a membrane-bound O-acyltransferase responsible for palmitoylating Wnt proteins, which is essential for their signaling ability and secretion. At 5 µM, IWP-4 has been shown to...
| Schlagworte: | Inhibitor of Wnt Production-4,... |
| Anwendung: | Wnt production inhibitor, Porcupine inactivator |
| CAS | 686772-17-8 |
| MW: | 496.6 D |
ab 49,00 €
