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IWP-2
Artikelnummer: TGM-T2702-100mg
Description: IWP-2 is a Wnt pathway inhibitor (IC50=27 nM) and an ATP-competitive CK1delta inhibitor (IC50=40 nM for M82FCK1delta). IWP-2 inhibits self-renewal of embryonic stem cells and has been used in stem cell and organoid research. Target: Porcupine, Casein Kinase, Wnt/beta-catenin. Smiles:...
| Schlagworte: | IWP2 |
| CAS | 686770-61-6 |
| MW: | 466.6 D |
ab 45,00 €
IWP-2
Artikelnummer: Cay13951-1
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to beta-catenin activation of gene transcription. IWP-2 is an inhibitor of Wnt production...
| Schlagworte: | Inhibitor of Wnt Production-2,... |
| Anwendung: | Porcupine inactivator |
| CAS | 686770-61-6 |
| MW: | 466.6 D |
ab 36,00 €
IWP-2
Artikelnummer: LKT-I9060.5
IWP-2 is an inhibitor of PORCN that inhibits Wnt signaling, exhibiting anticancer activity. IWP-2 increases activity of caspases 3 and 7, inhibiting proliferation, migration, and invasion of gastric cancer cells and colorectal cancer cells.
| Schlagworte: | IWP2 |
| Anwendung: | Porcupine inactivator |
| CAS | 686770-61-6 |
| MW: | 466.6 D |
ab 95,00 €
