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PX-478
Artikelnummer: TGM-T6961-100mg
Description: PX-478 is a HIF-1alpha inhibitor with selectivity, oral activity, and blood-brain barrier permeability. PX-478 has antitumor activity and also protects pancreatic beta-cell function in diabetes mellitus and is used in type 2 diabetes mellitus research. Target: HIF, Autophagy, HIF/HIF...
| Schlagworte: | PX-478 2HCl |
| Anwendung: | HIF-1 alpha inhibitor |
| CAS | 685898-44-6 |
| MW: | 394.12 D |
ab 48,00 €
PX-478
Artikelnummer: Cay10005189-5
PX-478 suppresses both constitutive and hypoxia-induced levels of HIF-1alpha in cancer cells, resulting in reduced expression of HIF-1alpha target genes. It induces apoptosis in human tumor xenografts in mice to an extent that is proportional to initial HIF-1alpha level. PX-478 can also increase chemo- or...
| Schlagworte: | 4-[bis(2-chloroethyl)oxidoamino]-L-phenylalanine, dihydrochloride |
| Anwendung: | HIF-1 alpha inhibitor |
| CAS | 685898-44-6 |
| MW: | 394.1 D |
ab 79,00 €
