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(E/Z)-4-hydroxy Tamoxifen
(E/Z)-4-hydroxy Tamoxifen

Artikelnummer: Cay17308-50

(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen (Cay-13258). It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the...
Schlagworte: 4-hydroxy Tamoxifen, 4-OHT, Afimoxifene, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol
Anwendung: Active tamoxifen metabolite, estrogen receptor agonist/antagonist
CAS 68392-35-8
MW: 387.5 D
ab 43,00 €
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4-Hydroxytamoxifen
4-Hydroxytamoxifen

Artikelnummer: CDX-H0150-M050

RTECS: SL1210000 Source/Host Chemicals: Synthetic. Appearance: White to yellow powder. Solubility: Soluble in ethanol or methanol (both 5mg/ml). Identity: Determined by 1H-NMR. InChi Key: TXUZVZSFRXZGTL-QPLCGJKRSA-N Smiles: CC/C(C1=CC=CC=C1)=C(C2=CC=C(O)C=C2)/C3=CC=C(OCCN(C)C)C=C3 4-Hydroxytamoxifen is an active...
Schlagworte: Afimoxifene, 4-OHT, cis/trans-4-Hydroxytamoxifen, (E/Z)-4-Hydroxytamoxifen, HTMX,...
Anwendung: Active metabolite
CAS 68392-35-8
MW: 387.51 D
ab 174,00 €
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(E, Z)-4-Hydroxytamoxifen
(E, Z)-4-Hydroxytamoxifen

Artikelnummer: LKT-H9716.5

Mixture of cis- and trans-isomers of 4-hydroxytamoxifen.
Anwendung: Estrogen receptor 1 agonist/antagonist, Estrogen receptor 2 agonist/antagonist
CAS 68392-35-8
MW: 387.51 D
ab 77,00 €
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