Zu "68392-35-8" wurden 4 Artikel gefunden!
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(E/Z)-4-hydroxy Tamoxifen
Artikelnummer: Cay17308-50
(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen (Cay-13258). It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the...
| Schlagworte: | 4-hydroxy Tamoxifen, 4-OHT, Afimoxifene, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol |
| Anwendung: | Active tamoxifen metabolite, estrogen receptor agonist/antagonist |
| CAS | 68392-35-8 |
| MW: | 387.5 D |
ab 44,00 €
(E/Z)-4-Hydroxytamoxifen
Artikelnummer: TGM-T6743-100mg
Description: (E/Z)-4-Hydroxytamoxifen (Afimoxifene), the active metabolite of tamoxifen, is a selective estrogen receptor (ER) modulator widely used in the therapeutic and chemopreventive treatment of breast cancer. Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor. Smiles:...
| Schlagworte: | Afimoxifene, 4-Hydroxytamoxifen |
| Anwendung: | Antineoplastic |
| CAS | 68392-35-8 |
| MW: | 387.51 D |
ab 46,00 €
4-Hydroxytamoxifen
Artikelnummer: CDX-H0150-M050
RTECS: SL1210000 Source/Host Chemicals: Synthetic. Appearance: White to yellow powder. Solubility: Soluble in ethanol or methanol (both 5mg/ml). Identity: Determined by 1H-NMR. InChi Key: TXUZVZSFRXZGTL-QPLCGJKRSA-N Smiles: CC/C(C1=CC=CC=C1)=C(C2=CC=C(O)C=C2)/C3=CC=C(OCCN(C)C)C=C3 4-Hydroxytamoxifen is an active...
| Schlagworte: | Afimoxifene, 4-OHT, cis/trans-4-Hydroxytamoxifen, (E/Z)-4-Hydroxytamoxifen, HTMX,... |
| Anwendung: | Active metabolite |
| CAS | 68392-35-8 |
| MW: | 387.51 D |
ab 174,00 €
(E, Z)-4-Hydroxytamoxifen
Artikelnummer: LKT-H9716.5
Mixture of cis- and trans-isomers of 4-hydroxytamoxifen.
| Anwendung: | Estrogen receptor 1 agonist/antagonist, Estrogen receptor 2 agonist/antagonist |
| CAS | 68392-35-8 |
| MW: | 387.51 D |
ab 81,00 €
