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iCRT 14
iCRT 14

Artikelnummer: TGM-T4486-100mg

Description: iCRT 14 is a novel and potent inhibitor of beta-catenin-responsive transcription (CRT) with an IC50 of 40.3 nM in assays of Wnt pathway activity. Target: Wnt/beta-catenin. Smiles: Cc1cc(C=C2SC(=O)N(C2=O)c2ccccc2)c(C)n1-c1cccnc1. References: Gonsalves FC, et al. An RNAi-based chemical genetic screen...
Anwendung: beta-catenin inhibitor
CAS 677331-12-3
MW: 375.44 D
ab 31,00 €
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iCRT14
iCRT14

Artikelnummer: Cay22132-10

iCRT14 is a potent inhibitor of beta-catenin-responsive transcription (CRT) that inhibits Wnt signaling in a reporter assay in vitro (IC50 = 40.3 nM). It inhibits the interaction between beta-catenin and T cell factor 4 (Tcf4) in quantitative reporter assays of beta-catenin/Tcf4 binding (Ki = 53.51 µM). It inhibits...
Schlagworte: 5-[[2,5-dimethyl-1-(3-pyridinyl)-1H-pyrrol-3-yl]methylene]-3-phenyl-2,4-thiazolidinedione
Anwendung: beta-catenin inhibitor
CAS 677331-12-3
MW: 375.4 D
ab 133,00 €
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