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Gliotoxin
Artikelnummer: TGM-TN1694-10mg
Description: Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway. Gliotoxin is a mycotoxin produced by several moulds such as Aspergillus fumigatus. Gliotoxin activates PKA and increases...
| CAS | 67-99-2 |
| MW: | 326.39 D |
ab 140,00 €
Gliotoxin
Artikelnummer: Cay11433-1
Gliotoxin is an immunosuppressive mycotoxin produced by pathogenic strains of Aspergillus and other fungi with diverse biological activities. It inhibits 20S proteasomal chymotrypsin activity (IC50 = 10 µM), blocking the degradation of IkappaBalpha and preventing the activation of NF-kappaB. Gliotoxin induces...
| Schlagworte: | Aspergillin, 2,3R,5aS,6S-tetrahydro-6-hydroxy-3-(hydroxymethyl)-2-methyl-10H-3,10aR-epidithiopyrazino[1,2-a]indole-1,4-dione |
| Anwendung: | Immunosuppressive mycotoxin |
| CAS | 67-99-2 |
| MW: | 326.4 D |
ab 77,00 €
