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Talniflumate
Talniflumate

Artikelnummer: TGM-T4503-100mg

Description: Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell culture. It possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. It also increases...
Schlagworte: Somalgen
Anwendung: Analgesic, Antiinflammatory
CAS 66898-62-2
MW: 414.33 D
ab 31,00 €
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Talniflumate
Talniflumate

Artikelnummer: Cay29623-5

Talniflumate is a prodrug form of the COX-2 inhibitor niflumic acid (Cay-70650). It decreases the rate of chloride/bicarbonate exchange by 55% in isolated mouse intestinal villous epithelial cells when used at a concentration of 100 µM. Dietary administration of talniflumate (88 mg/kg per day) increases survival but...
Schlagworte: BA 7602-06, 2-[[3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester
Anwendung: COX-2 inhibitor prodrug (niflumic acid)
CAS 66898-62-2
MW: 414.3 D
ab 53,00 €
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