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Kevetrin hydrochloride
Artikelnummer: TGM-T3184-100mg
Description: Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity. Target: p53, Mdm2. Smiles: Cl.NC(=N)SCCCC#N. References: Han D., Smalley K. (2015) Targeting the Cell Cycle and p53 in...
| Schlagworte: | 4-Isothioureidobutyronitrile hydrochloride, thioureido butyronitrile hydrochloride, Thioureidobutyronitrile HCl |
| Anwendung: | p53 activator |
| CAS | 66592-89-0 |
| MW: | 179.67 D |
ab 38,00 €
Kevetrin (hydrochloride)
Artikelnummer: Cay28288-10
Kevetrin is an activator of p53. It increases levels of activated p53 and expression of p21 in A549 cells and decreases expression of the transcription factor E2F1 in a variety of cell lines. Kevetrin decreases cell viability in a panel of cancer cell lines with a mean IC50 value of 0.49 µM. It reduces tumor growth...
| Schlagworte: | 4-Isothioureidobutyronitrile, NSC 525990, carbamimidothioic acid, 3-cyanopropyl ester, monohydrochloride |
| Anwendung: | p53 activator |
| CAS | 66592-89-0 |
| MW: | 179.7 D |
ab 84,00 €
