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NCI 126224
Artikelnummer: TGM-T83895-10mg
Description: NCI 126224, a toll-like receptor 4 (TLR4) antagonist, demonstrates selective inhibition of nitric oxide (NO) production in RAW 264.7 macrophages, triggered by the TLR4 agonist LPS (IC50 = 0.31 µM), as opposed to minimal effects on NO production induced by agonists for TLR7/8 (R-848), TLR1/2 (Pam3CSK4),...
| Schlagworte: | NSC 126224 |
| Anwendung: | TLR4 antagonist |
| CAS | 65974-52-9 |
| MW: | 265.2 D |
ab 86,00 €
NCI 126224
Artikelnummer: Cay39520-1
NCI 126224 is a toll-like receptor 4 (TLR4) antagonist. NCI 126224 selectively inhibits nitric oxide (NO) production induced by the TLR4 agonist LPS (IC50 = 0.31 µM) over the TLR7/8 agonist R-848 (Cay-14806), TLR1/2 agonist Pam3CSK4 (Cay-24126), and TLR3 agonist poly(I:C) in RAW 264.7 macrophages but also inhibits...
| Schlagworte: | NSC 126224, 2-[(2-nitrophenyl)methylene]-propanedioic acid, 1,3-dimethyl ester |
| Anwendung: | TLR4 antagonist |
| CAS | 65974-52-9 |
| MW: | 265.2 D |
ab 34,00 €
