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SU11274
Artikelnummer: TGM-T6154-100mg
Description: SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRbeta, EGFR or Tie2. Target: Apoptosis, c-Met/HGFR, CDK, Autophagy, VEGFR, FGFR. Smiles: C(=C\1/C=2C(NC1=O)=CC=C(S(N(C)C3=CC(Cl)=CC=C3)(=O)=O)C2)\C4=C(C)C(C(=O)N5CCN(C)CC5)=C(C)N4....
| Schlagworte: | PKI-SU11274, Met Kinase Inhibitor |
| Anwendung: | c-Met inhibitor |
| CAS | 658084-23-2 |
| MW: | 568.09 D |
ab 40,00 €
SU11274
Artikelnummer: Cay14861-1
MET is a proto-oncogene which encodes the hepatocyte growth factor receptor c-Met. It has normal roles in morphogenesis, migration, apoptosis, and angiogenesis. Dysregulation of c-Met occurs in many types of cancer. SU11274 is a potent, selective, ATP-competitive inhibitor of c-Met (IC50 = 20 nM). It has much less...
| Schlagworte: | Met Kinase Inhibitor,... |
| Anwendung: | c-Met inhibitor |
| CAS | 658084-23-2 |
| MW: | 568.1 D |
ab 61,00 €
