Zu "64-77-7" wurden 2 Artikel gefunden!
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Tolbutamide
Artikelnummer: TGM-T1054-1g
Description: Tolbutamide (HLS 831) is a sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPA MIDE. Target: Autophagy, Potassium Channel. Smiles: S(NC(NCCCC)=O)(=O)(=O)C1=CC=C(C)C=C1. References: Wray HL, et al, Biochem Biophys Res Commun. 1973, 53(1), 291-294.
| Schlagworte: | HLS 831 |
| CAS | 64-77-7 |
| MW: | 270.35 D |
ab 43,00 €
Tolbutamide
Artikelnummer: Cay19888-50
Tolbutamide is an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.9 µM). It is selective for SUR1/Kir6.2 over SUR2A/Kir6.2 and SUR2B/Kir6.2 channels (IC50s = 85 and 88 µM, respectively). Tolbutamide increases glucose-induced insulin secretion and calcium influx...
| Schlagworte: | D 860, NSC 23813, NSC 87833, U-2043, N-[(butylamino)carbonyl]-4-methyl-benzenesulfonamide |
| Anwendung: | ABCC8 inhibitor |
| CAS | 64-77-7 |
| MW: | 270.3 D |
ab 47,00 €
