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ONO-7300243
ONO-7300243

Artikelnummer: TGM-T7393-100mg

Description: ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1, IC50 : 0.16 µM). Target: LPA Receptor, LPL Receptor. Smiles: COc1cc(cc(OC)c1C)C(=O)N(CCCc1ccccc1)Cc1ccc(CC(O)=O)cc1. References: Terakado M , Suzuki H , Hashimura K , et al. Discovery of ONO-7300243 from a novel class of...
Anwendung: LPA1 antagonist
CAS 638132-34-0
MW: 461.55 D
ab 40,00 €
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ONO-7300243
ONO-7300243

Artikelnummer: Cay22052-1

ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1, IC50 = 0.16 µM). It is selective for LPA1 over the LPA2 and LPA3 receptors (IC50s = 8.6 and >10 µM, respectively). ONO-7300243 dose-dependently reduces intraurethral pressure induced by LPA in rats (ID50 = 11.6 mg/kg) without affecting mean...
Schlagworte: 4-[[(3,5-dimethoxy-4-methylbenzoyl)(3-phenylpropyl)amino]methyl]-benzeneacetic acid
Anwendung: LPA1 antagonist
CAS 638132-34-0
MW: 461.6 D
ab 55,00 €
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