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SU14813
Artikelnummer: TGM-T7945-100mg
Description: SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRbeta and KIT). Target: c-Kit, VEGFR, PDGFR. Smiles: Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCC(O)CN1CCOCC1. References: Patyna S, et al....
| Anwendung: | Dual VEGFR / PDGFR family kinase inhibitor |
| CAS | 627908-92-3 |
| MW: | 442.48 D |
ab 47,00 €
SU 14813
Artikelnummer: Cay31514-100
SU 14813 is a dual VEGFR and PDGFR family kinase inhibitor (IC50s = 0.002, 0.05, 0.004, and 0.015 µM for VEGFR1, VEGFR2, PDGFRbeta, and KIT, respectively). It is selective for these kinases over FGFR1, EGFR, Src, and c-Met (IC50s = 3.5, >20, 2.5, and 9 µM, respectively). SU 14813 inhibits VEGFR2, PDGFRbeta, KIT, and...
| Schlagworte: | 5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrro... |
| Anwendung: | Dual VEGFR / PDGFR family kinase inhibitor |
| CAS | 627908-92-3 |
| MW: | 442.5 D |
ab 77,00 €
