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JNJ-10198409
JNJ-10198409

Artikelnummer: TGM-T15616-100mg

Description: JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-beta kinase (IC50=4.2 nM) and PDGFR-alpha kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. Target: PDGFR. Smiles:...
Schlagworte: JNJ-10198409
Anwendung: PDGF-BB inhibitor
CAS 627518-40-5
MW: 325.34 D
ab 30,00 €
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JNJ-10198409
JNJ-10198409

Artikelnummer: Cay10008131-1

Inhibition of the tyrosine kinase activity of growth factor receptors such as the platelet-derived growth factor (PDGF-BB) receptor can have potent antiangiogenic and antiproliferative activity. JNJ-10198409 is a small molecule inhibitor of platelet-derived growth factor (PDGF-BB) tyrosine kinase with an IC50 value...
Schlagworte: N-(3-fluorophenyl)-1,4-dihydro-6,7-dimethoxy-indeno[1,2-c]pyrazol-3-amine
Anwendung: PDGF-BB inhibitor
CAS 627518-40-5
MW: 325.3 D
ab 39,00 €
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