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JNJ-10198409
Artikelnummer: TGM-T15616-100mg
Description: JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-beta kinase (IC50=4.2 nM) and PDGFR-alpha kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. Target: PDGFR. Smiles:...
| Schlagworte: | JNJ-10198409 |
| Anwendung: | PDGF-BB inhibitor |
| CAS | 627518-40-5 |
| MW: | 325.34 D |
ab 30,00 €
JNJ-10198409
Artikelnummer: Cay10008131-1
Inhibition of the tyrosine kinase activity of growth factor receptors such as the platelet-derived growth factor (PDGF-BB) receptor can have potent antiangiogenic and antiproliferative activity. JNJ-10198409 is a small molecule inhibitor of platelet-derived growth factor (PDGF-BB) tyrosine kinase with an IC50 value...
| Schlagworte: | N-(3-fluorophenyl)-1,4-dihydro-6,7-dimethoxy-indeno[1,2-c]pyrazol-3-amine |
| Anwendung: | PDGF-BB inhibitor |
| CAS | 627518-40-5 |
| MW: | 325.3 D |
ab 39,00 €
