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MK-0812
MK-0812

Artikelnummer: TGM-TQ0182-10mg

Description: MK-0812 is an effective and specific CCR2 antagonist. Target: CCR. Smiles: [H][C@]1(CC[C@](C1)(C(C)C)C(=O)N1CCc2ncc(cc2C1)C(F)(F)F)N[C@@]1([H])CCOC[C@@]1([H])OC. References: Wisniewski T, et al. Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a...
Anwendung: CCR2 antagonist
CAS 624733-88-6
MW: 469.54 D
ab 181,00 €
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MK-0812
MK-0812

Artikelnummer: Cay21803-5

MK-0812 is an antagonist of chemokine (C-C) motif receptor 2 (CCR2, IC50 = 5 nM for the human receptor). It inhibits mammosphere formation of BT-549 breast cancer cells, an effect that is enhanced by the beta-catenin inhibitor PNU 74654 (Cay-16349). MK-0812 (0.03, 0.1, and 0.3 mg/kg) increases chemokine (C-C) motif...
Schlagworte: 1,5-anhydro-2,3-dideoxy-3-[[(1R,3S)-...
Anwendung: CCR2 antagonist
CAS 624733-88-6
MW: 469.5 D
ab 100,00 €
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