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VU0364770
Artikelnummer: TGM-T6727-100mg
Description: VU0364770 (VU 0364770)(EC50=1.1 µM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGlu subtypes. Target: GluR. Smiles: Clc1cccc(NC(=O)c2ccccn2)c1. References: Jones CK, et al. J Pharmacol Exp Ther, 2012, 340(2), 404-421.
| Schlagworte: | VU 0364770 |
| Anwendung: | mGluR4 postitive allosteric modulator |
| CAS | 61350-00-3 |
| MW: | 232.67 D |
ab 31,00 €
VU0364770
Artikelnummer: Cay22927-10
VU0364770 is a positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4, EC50 = 1.1 µM in a calcium mobilization assay). It is also a positive allosteric modulator of mGluR6 (EC50 = 6.8 µM) and an antagonist of mGluR5 (IC50 = 17.9 µM). VU0364770 binds to monoamine oxidase A (MAO-A) and MAO-B (Kis =...
| Schlagworte: | N-(3-chlorophenyl)-2-pyridinecarboxamide |
| Anwendung: | mGluR4 postitive allosteric modulator |
| CAS | 61350-00-3 |
| MW: | 232.7 D |
ab 111,00 €
