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AKT inhibitor VIII
Artikelnummer: TGM-T3346-100mg
Description: AKT inhibitor VIII (AKTi-1/2) is a highly specific inhibitor of Akt1/2, with IC50 values of 58 nM and 210 nM respectively, demonstrating approximately 36-fold greater selectivity for Akt1 over Akt3. Target: Apoptosis, Akt. Smiles: O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(cc2)-c2nc3cc4[nH]cnc4cc3nc2-c2ccccc2)CC1....
| Schlagworte: | AKTi-1/2 |
| Anwendung: | Akt1/Akt2 inhibitor |
| CAS | 612847-09-3 |
| MW: | 551.64 D |
ab 44,00 €
Akt Inhibitor VIII
Artikelnummer: Cay14870-1
Akt inhibitor VIII is a potent allosteric inhibitor of Akt1 and Akt2 (IC50s = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 µM). It is a poor or ineffective inhibitor of a wide range of other serine-threonine kinases. Akt inhibitor VIII is cell permeable, blocking insulin...
| Schlagworte: | 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Anwendung: | AKT1 / AKT2 inhibitor |
| CAS | 612847-09-3 |
| MW: | 551.7 D |
ab 39,00 €
