Zu "608141-41-9" wurden 3 Artikel gefunden!
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Apremilast
Artikelnummer: TGM-T2923-100mg
Description: Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities. Target: PDE, TNF, Apoptosis. Smiles: [C@H](CS(C)(=O)=O)(N1C(=O)C=2C(C1=O)=CC=CC2NC(C)=O)C3=CC(OCC)=C(OC)C=C3. References: Perez-Aso M, et al. Apremilast, a novel phosphodiesterase 4...
| Schlagworte: | CC-10004 |
| Anwendung: | Targets cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] (PDE4) |
| CAS | 608141-41-9 |
| MW: | 460.5 D |
ab 43,00 €
Apremilast
Artikelnummer: Cay18502-5
Apremilast is an inhibitor of phosphodiesterase 4 (PDE4) with an IC50 value of 74 nM when tested in U937 cell lysates with 1 mM cAMP. It is orally active, significantly decreasing epidermal thickness and epithelial cell proliferation index in a mouse model of psoriasis. Apremilast reduces both TNF-alpha and matrix...
| Schlagworte: | CC-10004, N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-acetamide |
| Anwendung: | PDE4 inhibitor |
| CAS | 608141-41-9 |
| MW: | 460.5 D |
ab 88,00 €
Apremilast
Artikelnummer: LKT-A6269.1
PDE4 inhibitor.
| Schlagworte: | CC-10004, CC10004 |
| Anwendung: | Phosphodiesterase (PDE) IV inhibitor |
| CAS | 608141-41-9 |
| MW: | 460.51 D |
ab 108,00 €
