Zu "607742-69-8" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Intepirdine
Artikelnummer: TGM-T1774-100mg
Description: Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer's Disease. Target: 5-HT Receptor. Smiles: S(=O)(=O)(C1=CC2=C(C(=CC=C2)N3CCNCC3)N=C1)C4=CC=CC=C4. References: Chuang ATT, et al. Alzheimers Dement, 2006, 2, S631-S632 (abstract).
| Schlagworte: | RVT-101, SB 742457, GSK-742457 |
| Anwendung: | Dementia therapeutic agent |
| CAS | 607742-69-8 |
| MW: | 353.44 D |
ab 34,00 €
SB-742457
Artikelnummer: Cay22200-1
SB-742457 is an orally bioavailable antagonist of the serotonin (5-HT) receptor subtype 5-HT6 (Ki = 1.4 nM). SB-742457 (1 µM) also binds to 5-HT1B, 5-HT2A, 5-HT2B, and 5-HT2C receptors with high affinity. SB-742457 reduces 5-HT6 activation of Gs-mediated cAMP production in a concentration-dependent manner with an...
| Schlagworte: | GSK742457, 3-(phenylsulfonyl)-8-(1-piperazinyl)-quinoline |
| Anwendung: | 5-HT6 receptor antagonist |
| CAS | 607742-69-8 |
| MW: | 353.4 D |
ab 52,00 €
